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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DMD All Species: 1.82
Human Site: T279 Identified Species: 4
UniProt: P11532 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11532 NP_004009.1 3685 426692 T279 M H Y S Q Q I T V S L A Q G Y
Chimpanzee Pan troglodytes XP_001172869 3433 394222 S249 S I I M Y L T S L F E V L P Q
Rhesus Macaque Macaca mulatta XP_001096514 2514 292248
Dog Lupus familis XP_855595 3557 411174 D249 A Q G E I S N D V E E V K E Q
Cat Felis silvestris
Mouse Mus musculus P11531 3678 425799 V281 H Y S Q Q I T V S L A Q G Y E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506998 3432 393824 E251 N T A P E E H E G L R A E T P
Chicken Gallus gallus P11533 3660 422863 E281 H Q Q H F S Q E I T V N I P Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001332965 2677 308332
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDW6 3598 410396 T270 V P L D N D Q T S L G L Y T S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW65 3674 417408 P267 H K M L S S Q P S T S S S S A
Sea Urchin Strong. purpuratus NP_999661 3908 447496 S297 A S P D L S L S D M S E I D I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.5 66.2 91.7 N.A. 91 N.A. N.A. 47.5 78.4 N.A. 39.8 N.A. 29.3 N.A. 22 35.5
Protein Similarity: 100 66.6 67 94.1 N.A. 95.3 N.A. N.A. 66.2 88.7 N.A. 54.5 N.A. 49.5 N.A. 42.8 57.1
P-Site Identity: 100 0 0 6.6 N.A. 6.6 N.A. N.A. 6.6 0 N.A. 0 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 13.3 0 13.3 N.A. 13.3 N.A. N.A. 26.6 20 N.A. 0 N.A. 13.3 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 10 0 0 0 0 0 0 0 10 19 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 10 0 10 10 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 10 10 0 19 0 10 19 10 10 10 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 10 0 10 0 10 10 0 % G
% His: 28 10 0 10 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 10 10 10 0 10 0 0 0 19 0 10 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 10 10 10 10 10 0 10 28 10 10 10 0 0 % L
% Met: 10 0 10 10 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 10 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 10 10 0 0 0 10 0 0 0 0 0 19 10 % P
% Gln: 0 19 10 10 19 10 28 0 0 0 0 10 10 0 28 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 10 10 10 10 37 0 19 28 10 19 10 10 10 10 % S
% Thr: 0 10 0 0 0 0 19 19 0 19 0 0 0 19 0 % T
% Val: 10 0 0 0 0 0 0 10 19 0 10 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 10 0 0 0 0 0 0 0 10 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _